PLCOm2012: Selection criteria for lung cancer screening
In the United States the National Lung Screening Trial (NLST) used risk factors for lung cancer (e.g., ≥30 pack-years of smoking and <15 years since quitting) as selection criteria for lung-cancer screening. Use of an accurate model that incorporates additional risk factors to select persons for screening may identify more persons who have lung cancer or in whom lung cancer will develop.
Research authors: Martin C. Tammemägi, Hormuzd A. Katki, William G. Hocking, Timothy R. Church, Neil Caporaso, Paul A. Kvale, Anil K. Chaturvedi, Gerard A. Silvestri, Tom L. Riley, John Commins, Christine D. Berg
Version: 1.6
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  • Pulmonology
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The calculated 6-year risk of lung cancer is:

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The use of the PLCOM2012 model was shown to be more sensitive than the NLST criteria for lung-cancer detection.


Outcomes of the model can be used for the selection of individuals for lung cancer screening.

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