Delirium (PRE-DELIRIC) prediction model for intensive care patients, version 2 (recalibrated)
The recalibrated PRE-DELIRIC model (version 2) for intensive care patients consists of 10 risk factors that are readily available within 24 hours after intensive care admission and has a high predictive value. The model allows for early prediction of delirium and initiation of preventive measures.
Research authors: van den Boogaard M, Schoonhoven L, Maseda E, Plowright C, Jones C, Luetz A, Sackey PV, Jorens PG, Aitken LM, van Haren FM, Donders R, van der Hoeven JG, and Pickkers P.
Version: 1.24
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  • Intensive care
  • Logistic regression
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Age

18
90
years

APACHE-II score

1
100
points

Urea concentration

1
50
mmol/L

Administered morphine dosis

0
100
mg/day

Use of sedatives

Metabolic acidosis

Coma

Urgent admission

Admission category

Infection

Risk of delirium in intensive care unit patient: ...

Calculating...

How this model should be used: 
The recalibrated PRE-DELIRIC model (version 2) for intensive care patients consists of ten risk factors that are readily available within 24 hours afterintensive care admission and has a high predictive value. The model allows for early prediction of delirium and initiation of preventive measures.1

Model performance: 
An international multicenter validation study of a previously developed model2 was performed including 1,824 ICU patients. Although the incidence of all ten predictors differed significantly between centers, the area under the receiver operating characteristic (AUROC) curve of the eight participating centers remained good: 0.77 (95 % CI 0.74–0.79). Recalibration resulted in improved re-calibration of the PRE-DELIRIC model.
 
Source: 
[1] van den Boogaard M, Pickkers P, Slooter AJ, et al. Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu patients) delirium prediction model for intensive care patients: observational multicentre study. BMJ. 2012;344:e420.
[2] van den Boogaard M, Schoonhoven L, Maseda E, et al. Recalibration of the delirium prediction model for ICU patients (PRE-DELIRIC): a multinational observational study. Intensive Care Med. 2014;40(3):361-9. 
 

Figure 1. Calibration belt before (a) and after (b) model recalibration (van den Boogaard et al, 2014).

This model is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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