The current model showed an area under the curve of 0.85 (95% CI: 0.818 - 0.911) on internal validation. Where SVI prediction on mpMRI alone showed an AUC of 0.59 (95% CI: 0.540 - 0.643).
Decision curve analysis showed a benefit of applying the model in clinical practice with threshold probabilities ≤25%.
Internal validation showed a slight miscalibration of predicted SVI probabilities >40%. However, it is highly unlikely that surgeons will attempt a conservative approach to the seminal vesicles if the risk of involvement is higher than 40%.
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