Risk of bleeding during anticoagulant treatment for venous thromboembolism - Evidencio
Risk of bleeding during anticoagulant treatment for venous thromboembolism
With the use of 3 easily obtainable, clinical variables, this prediction model identifies a subgroup of patients at the start of anticoagulant therapy who have a high risk of developing hemorrhagic complications.
Autores de la investigación: Kuijer PM, Hutten BA, Prins MH, and Büller HR.
Versión: 1.14
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Información condicional

Clinical implications:
The findings of the underlying study by Kuijer et al (1999) indicate that with several simple, easily obtainable clinical variables, it is possible to identify a subgroup of patients at the start of anticoagulant therapy who have a high risk of developing hemorrhagic complications.

Model performance: 
In patients treated for VTE, our model categorized approximately one fifth of the patients to be at high risk for bleeding complications. In this group, the incidence of all bleeding complications during anticoagulant therapy was 17%, of which more than one third met the criteria for major bleeding. These rates were about 6 to 7 times higher than the rates observed in those identified as low risk. This difference in bleeding incidence was not due to differences in the intensity of anticoagulant treatment among the various risk categories.

Source:

  1. Kuijer PM, Hutten BA, Prins MH, et al. Prediction of the risk of bleeding during anticoagulant treatment for venous thromboembolism. Arch Intern Med. 1999;159(5):457-60.

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