Risk score for detecting insignificant prostate cancer in unscreened patien - Evidencio
Risk score for detecting insignificant prostate cancer in unscreened patient cohorts
This risk score was developed to differentiate between insignificant and significant prostate cancer in patients with Gleason 3+3 or lower prostate cancer in the preoperative setting. It allows users to select the desired sensitivity and specificity levels for detecting insignificant prostate cancer using two different cut-offs:
 
  • Cut-off 1: By selecting this cut-off value the calculator will have a sensitivity and specificity of 90% and 41% in detecting insignificant cancer, respectively. This setting is aimed at reducing the risk of over-treatment as much as possible (improved detection of true positive results).
 
  • Cut-off 2: By selecting this cut-off value the calculator will have a sensitivity and specificity of 38% and 90% in detecting insignificant cancer, respectively. This setting is aimed at reducing the risk of missing a significant PCa as much as possible (improved detection of true negative results).
Research authors: Dutto L, Ahmad A, Urbanova K, Wagner C, Schuette A, Addali M, Kelly JD, Shridhar A, Nathan S, Briggs TP, Witt JH, Shaw G
Version: 1.113
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  • Urology
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Relative odds of having insignificant PCa, compared to study population:

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