IBTR! 2.0: 10-year Ipsilateral Breast Tumor Recurrence
The Ipsilateral Breast Tumor Recurrence (IBTR) 2.0 is designed for use by physicians to guide medical decision-making regarding the use of radiation therapy in breast cancer patients who have undergone breast conserving surgery and appropriate axillary evaluation. This model calculates an evidence-based estimate of the 10-year ipsilateral breast tumor recurrence risk with and without the addition of whole breast radiation therapy. 

The IBTR 2.0 is not intended for use in the post-mastectomy setting, and it is not meant to address patients with multicentric disease or with in-situ only disease. It is assumed that all pathological specimens have been microscopically assessed with current histopathological standards. It is presumed that patients who are lymph node positive (with the exception of micrometastatic lymph node disease) will receive systemic therapy, either chemotherapy or hormonal therapy. The calculated benefit of hormonal therapy in this model is based on the tamoxifen literature and has been extrapolated to the use of aromatase inhibitors. Recent studies indicate that aromatase inhibitors have a similar, and possibly a slightly superior, impact on local control. 
Research authors: Mona Sanghani, Pauline T. Truong, Rita Abi Raad, Andrzej Niemierko, Mary Lesperance, Ivo A. Olivotto, David E. Wazer, Alphonse G. Taghian
Version: 1.3
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This model is provided for educational, training and information purposes. It must not be used to support medical decision making, or to provide medical or diagnostic services. Read our full disclaimer.

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