SAVE score: Survival After veno-arterial extracorporeal membrane oxygenation (ECMO)
Using a large international cohort of 3846 patients treated with extracorporeal membrane oxygenation ECMO for cardiogenic shock, prognostic factors were identified for hospital survival and a well calibrated and discriminatory survival prediction score was created comprising 13 pre-ECMO variables (the survival after veno-arterial-ECMO (SAVE)-score). It is the first validated international predictive mortality model based on a large population of acute refractory cardiogenic shock patients requiring ECMO. Based on these findings, the SAVE-score offers a validated tool to predict survival for patients receiving ECMO for refractory cardiogenic shock.
Research authors: Matthieu Schmidt, Aidan Burrell, Lloyd Roberts, Michael Bailey, Jayne Sheldrake, Peter T. Rycus, Carol Hodgson, Carlos Schneikestel, D. Jamie Cooper, Ravi R. Thiagarajan, Daniel Brodie, Vincent Pellegrino, David Pilcher
Version: 1.10
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The calculated SAVE score is: Points

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The SAVE score identifies five risk classes: 

  • Class I (Save score: ≥ 5). Survival rate 75%
  • Class II (Save score: 1 to 4). Survival rate 58%
  • Class III (Save score: -4 to 0). Survival rate 42%
  • Class IV (Save score: -9 to -5). Survival rate 30%
  • Class V (Save score: ≤ -10). Survival rate 18%

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